Evolutionary Design of Genetic Circuits and Cell-Cell Communications
نویسندگان
چکیده
YOHEI YOKOBAYASHI∗, CYNTHIA H. COLLINS∗, JARED R. LEADBETTER†, RON WEISS‡ and FRANCES H. ARNOLD∗,∗∗ ∗Division of Chemistry and Chemical Engineering, †Division of Engineering and Applied Science, California Institute of Technology 1200 E. California Blvd, Pasadena, CA 91125, USA ∗∗[email protected] ‡Department of Electrical Engineering, Princeton University, B-312, E-Quad, Princeton, NJ 08544, USA ‡[email protected]
منابع مشابه
A Fast and Self-Repairing Genetic Programming Designer for Logic Circuits
Usually, important parameters in the design and implementation of combinational logic circuits are the number of gates, transistors, and the levels used in the design of the circuit. In this regard, various evolutionary paradigms with different competency have recently been introduced. However, while being advantageous, evolutionary paradigms also have some limitations including: a) lack of con...
متن کاملAn Improved Standard Cell Placement Methodology using Hybrid Analytic and Heuristic Techniques
In recent years, size of VLSI circuits is dramatically grown and layout generation of current circuits has become a dominant task in design flow. Standard cell placement is an effective stage of physical design and quality of placement affects directly on the performance, power consumption and signal immunity of design. Placement can be performed analytically or heuristically. Analytical placer...
متن کاملInvestigation of Game Between Cells in Occurrence of Genetic Mutations Using Evolutionary Game Theory
In this paper, two games that play a role in creating a cancer tumor and suppression are studied using evolutionary game theory and its different modes are analyzed. The first game is the competition between a cancer cell and a healthy cell to receive food through the blood. In the second game, the interaction between the two oncogenes Ras and Myc is examined for cellular deformation
متن کاملSynthetic Biology Based on Genetic Logic Circuit, Using the Expression of Drug Resistance, BCRP Pump in MCF-7 Cancer Cell Line
Biological circuits are developed as biological parts within a cell to carry out logical functions resembling those studied in electronics circuits. These circuits can be performed as a method to vary cellular functions, to develop cellular responses to environmental conditions, or to regulate cellular developments. This research explored the possibility of synthetic biology based on the geneti...
متن کاملSynthetic Biology Based on Genetic Logic Circuit, Using the Expression of Drug Resistance, BCRP Pump in MCF-7 Cancer Cell Line
Biological circuits are developed as biological parts within a cell to carry out logical functions resembling those studied in electronics circuits. These circuits can be performed as a method to vary cellular functions, to develop cellular responses to environmental conditions, or to regulate cellular developments. This research explored the possibility of synthetic biology based on the geneti...
متن کاملA Continuous Plane Model to Machine Layout Problems Considering Pick-Up and Drop-Off Points: An Evolutionary Algorithm
One of the well-known evolutionary algorithms inspired by biological evolution is genetic algorithm (GA) that is employed as a robust and global optimization tool to search for the best or near-optimal solution with the search space. In this paper, this algorithm is used to solve unequalsized machines (or intra-cell) layout problems considering pick-up and drop-off (input/output) points. Such p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Advances in Complex Systems
دوره 6 شماره
صفحات -
تاریخ انتشار 2003